Review



targeting vector  (New England Biolabs)


Bioz Verified Symbol New England Biolabs is a verified supplier
Bioz Manufacturer Symbol New England Biolabs manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 96
      Buy from Supplier

    Structured Review

    New England Biolabs targeting vector
    Targeting Vector, supplied by New England Biolabs, used in various techniques. Bioz Stars score: 96/100, based on 1386 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/targeting vector/product/New England Biolabs
    Average 96 stars, based on 1386 article reviews
    targeting vector - by Bioz Stars, 2026-06
    96/100 stars

    Images



    Similar Products

    control vector  (Genecopoeia)
    93
    Genecopoeia control vector
    Control Vector, supplied by Genecopoeia, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/control vector/product/Genecopoeia
    Average 93 stars, based on 1 article reviews
    control vector - by Bioz Stars, 2026-06
    93/100 stars
    		  Buy from Supplier
    targeting vector  (New England Biolabs)
    96
    New England Biolabs targeting vector
    Targeting Vector, supplied by New England Biolabs, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/targeting vector/product/New England Biolabs
    Average 96 stars, based on 1 article reviews
    targeting vector - by Bioz Stars, 2026-06
    96/100 stars
    		  Buy from Supplier
    candidate target proteins ar tic le in pr es s recombinant pcold i expression vectors  (Sangon Biotech)
    86
    Sangon Biotech candidate target proteins ar tic le in pr es s recombinant pcold i expression vectors
    Candidate Target Proteins Ar Tic Le In Pr Es S Recombinant Pcold I Expression Vectors, supplied by Sangon Biotech, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/candidate target proteins ar tic le in pr es s recombinant pcold i expression vectors/product/Sangon Biotech
    Average 86 stars, based on 1 article reviews
    candidate target proteins ar tic le in pr es s recombinant pcold i expression vectors - by Bioz Stars, 2026-06
    86/100 stars
    		  Buy from Supplier
    adenoviral vectors targeting stard7  (Obio Technology Corp Ltd)
    86
    Obio Technology Corp Ltd adenoviral vectors targeting stard7
    Adenoviral Vectors Targeting Stard7, supplied by Obio Technology Corp Ltd, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/adenoviral vectors targeting stard7/product/Obio Technology Corp Ltd
    Average 86 stars, based on 1 article reviews
    adenoviral vectors targeting stard7 - by Bioz Stars, 2026-06
    86/100 stars
    		  Buy from Supplier
    lentiviral vectors targeting sec31a  (Genechem)
    86
    Genechem lentiviral vectors targeting sec31a
    Lentiviral Vectors Targeting Sec31a, supplied by Genechem, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/lentiviral vectors targeting sec31a/product/Genechem
    Average 86 stars, based on 1 article reviews
    lentiviral vectors targeting sec31a - by Bioz Stars, 2026-06
    86/100 stars
    		  Buy from Supplier
    non targeting control vectors shnc  (Genechem)
    86
    Genechem non targeting control vectors shnc
    Non Targeting Control Vectors Shnc, supplied by Genechem, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/non targeting control vectors shnc/product/Genechem
    Average 86 stars, based on 1 article reviews
    non targeting control vectors shnc - by Bioz Stars, 2026-06
    86/100 stars
    		  Buy from Supplier
    lentiviral vectors expressing shrna targeting gabaa receptor α1 subunit  (Genechem)
    86
    Genechem lentiviral vectors expressing shrna targeting gabaa receptor α1 subunit
    Lentiviral Vectors Expressing Shrna Targeting Gabaa Receptor α1 Subunit, supplied by Genechem, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/lentiviral vectors expressing shrna targeting gabaa receptor α1 subunit/product/Genechem
    Average 86 stars, based on 1 article reviews
    lentiviral vectors expressing shrna targeting gabaa receptor α1 subunit - by Bioz Stars, 2026-06
    86/100 stars
    		  Buy from Supplier
    halo targeting vector  (Addgene inc)
    93
    Addgene inc halo targeting vector
    Halo Targeting Vector, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/halo targeting vector/product/Addgene inc
    Average 93 stars, based on 1 article reviews
    halo targeting vector - by Bioz Stars, 2026-06
    93/100 stars
    		  Buy from Supplier
    shrna lentiviral vectors targeting circfrrs1  (Genechem)
    86
    Genechem shrna lentiviral vectors targeting circfrrs1
    Inhibition of <t>circFRRS1</t> alleviates the inflammation damage of PC-12 cells after H-OGD/R treatment. (A) Sequence diagram of circFRRS1. (B) The inhibition effects of si-circFRRS1 were detected by RT-PCR. (C) CCK8 assay revealed circFRRS1 inhibition improved the survival rate of H-OGD/R treated PC-12 cells. (D–F) The inhibition of circFRRS1 reduced the increasing level of TNF-α, IL-6, and IL-1β induced by H-OGD/R treatment. (G) The inhibition of circFRRS1 alleviated the NLRP3 inflammasome activation of H-OGD/R treated PC-12 cells. *** p < 0.001, vs. si-NC group; ## p < 0.01, ### p < 0.001, vs. H-OGD/R + si-NC group.
    Shrna Lentiviral Vectors Targeting Circfrrs1, supplied by Genechem, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/shrna lentiviral vectors targeting circfrrs1/product/Genechem
    Average 86 stars, based on 1 article reviews
    shrna lentiviral vectors targeting circfrrs1 - by Bioz Stars, 2026-06
    86/100 stars
    		  Buy from Supplier

    Image Search Results


    Inhibition of circFRRS1 alleviates the inflammation damage of PC-12 cells after H-OGD/R treatment. (A) Sequence diagram of circFRRS1. (B) The inhibition effects of si-circFRRS1 were detected by RT-PCR. (C) CCK8 assay revealed circFRRS1 inhibition improved the survival rate of H-OGD/R treated PC-12 cells. (D–F) The inhibition of circFRRS1 reduced the increasing level of TNF-α, IL-6, and IL-1β induced by H-OGD/R treatment. (G) The inhibition of circFRRS1 alleviated the NLRP3 inflammasome activation of H-OGD/R treated PC-12 cells. *** p < 0.001, vs. si-NC group; ## p < 0.01, ### p < 0.001, vs. H-OGD/R + si-NC group.

    Journal: Frontiers in Cellular Neuroscience

    Article Title: CircFRRS1 drives neuroinflammation through the miR-27a-3p/TLR4 pathway after deep hypothermic circulatory arrest

    doi: 10.3389/fncel.2026.1750887

    Figure Lengend Snippet: Inhibition of circFRRS1 alleviates the inflammation damage of PC-12 cells after H-OGD/R treatment. (A) Sequence diagram of circFRRS1. (B) The inhibition effects of si-circFRRS1 were detected by RT-PCR. (C) CCK8 assay revealed circFRRS1 inhibition improved the survival rate of H-OGD/R treated PC-12 cells. (D–F) The inhibition of circFRRS1 reduced the increasing level of TNF-α, IL-6, and IL-1β induced by H-OGD/R treatment. (G) The inhibition of circFRRS1 alleviated the NLRP3 inflammasome activation of H-OGD/R treated PC-12 cells. *** p < 0.001, vs. si-NC group; ## p < 0.01, ### p < 0.001, vs. H-OGD/R + si-NC group.

    Article Snippet: The shRNA lentiviral vectors targeting circFRRS1 (sh-circFRRS1) and the negative control (sh-NC) were obtained from Genechem (Shanghai, China).

    Techniques: Inhibition, Sequencing, Reverse Transcription Polymerase Chain Reaction, CCK-8 Assay, Activation Assay

    Dual luciferase reporter experiment confirmed the regulatory relationships of circFRRS1/rno-miR-27a-3p and rno-miR-27a-3p/TLR4 pairs. (A) The predicting binding site between circFRRS1 and miR-27a-3p. (B) Dual luciferase reporter assay revealed that miR-27a-3p attenuated the luciferase activity of circFRRS1-WT, but not of circFRRS1-MUT. (C) The predicting binding site between TLR4 and miR-27a-3p. (D) Dual luciferase reporter assay revealed that miR-27a-3p attenuated the luciferase activity of TLR4 3’-WT, but not of TLR4 3’-MUT. ** p < 0.01, *** p < 0.001, vs. control group; # p < 0.05, ### p < 0.001, vs. WT group.

    Journal: Frontiers in Cellular Neuroscience

    Article Title: CircFRRS1 drives neuroinflammation through the miR-27a-3p/TLR4 pathway after deep hypothermic circulatory arrest

    doi: 10.3389/fncel.2026.1750887

    Figure Lengend Snippet: Dual luciferase reporter experiment confirmed the regulatory relationships of circFRRS1/rno-miR-27a-3p and rno-miR-27a-3p/TLR4 pairs. (A) The predicting binding site between circFRRS1 and miR-27a-3p. (B) Dual luciferase reporter assay revealed that miR-27a-3p attenuated the luciferase activity of circFRRS1-WT, but not of circFRRS1-MUT. (C) The predicting binding site between TLR4 and miR-27a-3p. (D) Dual luciferase reporter assay revealed that miR-27a-3p attenuated the luciferase activity of TLR4 3’-WT, but not of TLR4 3’-MUT. ** p < 0.01, *** p < 0.001, vs. control group; # p < 0.05, ### p < 0.001, vs. WT group.

    Article Snippet: The shRNA lentiviral vectors targeting circFRRS1 (sh-circFRRS1) and the negative control (sh-NC) were obtained from Genechem (Shanghai, China).

    Techniques: Luciferase, Binding Assay, Reporter Assay, Activity Assay, Control

    The inhibition of circFRRS1 suppressed TLR4/NF-κB/NLRP3 pathway in H-OGD/R-induced PC-12 cells. (A) WB analysis revealed that the TLR4/NF-κB/NLRP3 axis was activated in H-OGD/R-induced PC-12 cells and markedly inhibited after si-circFRRS1 transfected. (B–G) Statistical analysis of WB results. * p < 0.05; ** p < 0.01, *** p < 0.001, vs. si-NC group; # p < 0.05, ## p < 0.01, vs. H-OGD/R + si-NC group.

    Journal: Frontiers in Cellular Neuroscience

    Article Title: CircFRRS1 drives neuroinflammation through the miR-27a-3p/TLR4 pathway after deep hypothermic circulatory arrest

    doi: 10.3389/fncel.2026.1750887

    Figure Lengend Snippet: The inhibition of circFRRS1 suppressed TLR4/NF-κB/NLRP3 pathway in H-OGD/R-induced PC-12 cells. (A) WB analysis revealed that the TLR4/NF-κB/NLRP3 axis was activated in H-OGD/R-induced PC-12 cells and markedly inhibited after si-circFRRS1 transfected. (B–G) Statistical analysis of WB results. * p < 0.05; ** p < 0.01, *** p < 0.001, vs. si-NC group; # p < 0.05, ## p < 0.01, vs. H-OGD/R + si-NC group.

    Article Snippet: The shRNA lentiviral vectors targeting circFRRS1 (sh-circFRRS1) and the negative control (sh-NC) were obtained from Genechem (Shanghai, China).

    Techniques: Inhibition, Transfection

    circFRRS1 can regulate TLR4 by targeting miR-27a-3p. (A) Administration of miR-27a-3p inhibitor could reverse the downregulation of TLR4 expression by transfecting si-circFRRS1. (B) Further protein-level detection using WB gave the further validation. *** p < 0.001, vs. si-NC group; # p < 0.05, ## p < 0.01, ### p < 0.001, vs. H-OGD/R + si-NC group or H-OGD/R + si-circ group.

    Journal: Frontiers in Cellular Neuroscience

    Article Title: CircFRRS1 drives neuroinflammation through the miR-27a-3p/TLR4 pathway after deep hypothermic circulatory arrest

    doi: 10.3389/fncel.2026.1750887

    Figure Lengend Snippet: circFRRS1 can regulate TLR4 by targeting miR-27a-3p. (A) Administration of miR-27a-3p inhibitor could reverse the downregulation of TLR4 expression by transfecting si-circFRRS1. (B) Further protein-level detection using WB gave the further validation. *** p < 0.001, vs. si-NC group; # p < 0.05, ## p < 0.01, ### p < 0.001, vs. H-OGD/R + si-NC group or H-OGD/R + si-circ group.

    Article Snippet: The shRNA lentiviral vectors targeting circFRRS1 (sh-circFRRS1) and the negative control (sh-NC) were obtained from Genechem (Shanghai, China).

    Techniques: Expressing, Biomarker Discovery